Opna Bio, South San Francisco, California.
Cancer Discov (2025) 15 (12): 2422–2430.
Department of Metabolism & Physiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.
AbstractBackground:. The sensitivity of a cancer screening biomarker to detect prevalent preclinical cancer drives screening benefit. Studies estimate sensitivity at different points in the biomarker ...
PARP inhibitor sensitivity is associated with cGAS–STING–IFN signaling, which can be harnessed by combining PARP inhibitors with STING agonists to overcome acquired resistance and requires NK cells to ...
Abstract. Molecular glue degrader (MGD) is an emerging therapeutic strategy offering an exciting alternative to traditional small molecules exploring new target space. These small molecules interact ...
The combination of anti-TROP2 ADCs with PD-(L)1 inhibitors represents a promising therapeutic strategy, merging targeted therapy with immunotherapy to improve treatment outcomes. Clinical trials are ...
MediLink Therapeutics (Suzhou) Co., Ltd., Suzhou, China.
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Affinity Biopharmaceutical Co., Ltd., Shanghai, China.
Washington University In St. Louis, St. Louis, MO.
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