Five key genes are linked with the most severe form of COVID-19, scientists said on Friday, in research that also pointed to several existing drugs that could be repurposed to treat people who risk ...

Scientists have created gene-edited pigs, goats and cattle to produce sperm with traits such as disease resistance and higher meat quality in what they say is a step towards genetically enhancing ...

Physiology or medicine was the third prize area Alfred Nobel mentioned in his will laying out his wishes for the Nobel Prize.

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The 2025 Nobel Prize in Physiology or Medicine has been awarded to American scientists Mary E. Brunkow and Fred Ramsdell, ...

RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...

In the post-genomic era, long non-coding RNAs (lncRNAs) have emerged as critical regulators in various cancers and hold potential as minimally invasive diagnostic biomarkers.

An interview with Philip Vanek, chief commercialization officer of the International Society for Cell & Gene Therapy (ISCT), reveals both promising developments and significant concerns shaping the ...

While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

Gene expression programs that establish and maintain specific cellular states are orchestrated through a regulatory network composed of transcription factors, cofactors, and chromatin regulators.

MicroRNAs (miRNAs) are critical regulators of the skeleton. In the growth plate, these small non-coding RNAs modulate gene networks that drive key stages of chondrogenesis, including proliferation, ...