For decades, scientists have fought cancer by developing small molecules to inhibit kinase enzymes. These enzymes play an important role in a host of cellular processes, including phosphorylation and ...

Tiny gold particles that act as carriers for lithium can be delivered directly to the brain in the form of a nasal spray.

Molecular dynamics simulations have emerged as an indispensable tool in modern biomedical research, particularly in the study of protein kinases. This computational approach permits detailed ...

Orelabrutinib, a highly selective CNS-penetrant, oral small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with best-in-class potential now ...

A study in Advanced Science has pinpointed how a high-salt diet can lead to cognitive decline. Researchers found excess salt ...

Phase I/II Trial Evaluating the Anti-Vascular Endothelial Growth Factor Monoclonal Antibody Bevacizumab in Combination With the HER-1/Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor ...

A recent study conducted by researchers at Queen Mary University of London unveiled a new mechanism through which cells ...

In the form of a 'nasal spray', tiny gold particles act as carriers, delivering a treatment directly to the brain: developed by scientists at the Università Rome campus/Fondazione Policlinico ...

The introduction of COVID-19 therapies containing ritonavir has markedly expanded the scope of use for this medicine. As a strong cytochrome P450 3A4 inhibitor, the use of ritonavir is associated with ...

Rapamycin became a billion-dollar drug, but many of the people instrumental to its discovery—including the people of Rapa Nui ...

Elderberry juice intake triggers metabolic gene expression changes, enhancing glucose control and fat oxidation in overweight ...