The Atlanta Falcons traveled to Santa Clara, California to take on the San Francisco 49ers on "Sunday Night Football." Here's what happened in Week 7.

The San Francisco 49ers suffered another major injury and didn’t have enough to overcome those issues in a Week 6 loss to the Tampa Bay Buccaneers.

Get a prediction, pick and odds for the NFL Week 8 matchup between the Houston Texans and the San Francisco 49ers.

USA Today's NFL experts make their picks for a Week 8 showdown between the Houston Texans and San Francisco 49ers

The Houston Texans receive unfortunate injury updates for the San Francisco 49ers game regarding Nico Collins and Christian Kirk.

Expert recap and game analysis of the San Francisco 49ers vs. Atlanta Falcons NFL game from October 19, 2025 on ESPN.

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce Huff (hamstring), wide receiver Ricky Pearsall Jr. (knee) and defensive lineman Yetur Gross-Matos (knee). Lenoir was questionable along with linebacker Luke Gifford (hamstring) as was guard/tackle Spencer Burford (knee).

Chase Lucas hasn't played much, but he's made an outsized impact for the 49ers, including two game-sealing plays.