Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy.

With starter Brock Purdy slowly working his way back from the right big toe injury that's kept him out since Week 4, the ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

If the 49ers win Sunday in Houston, they’ll match their overall win total from last season and they’ll be alone atop the NFC ...

How should George Kittle be used? What’s with the hamstring injuries? You’ve got questions, we act like we have answers.

Kyle Juszczyk’s wife, Kristin, attended the Week 7 game of the San Francisco 49ers and offered a glimpse of the outing in a ...

Despite being one of the most banged-up teams in the NFL, San Francisco sits tied atop the NFC West with the Seahawks and the ...

The 49ers are nearly halfway through the regular season, and their record is 5-2. And you are what your record says you are, ...

Mac Jones has been a massive addition to the San Francisco 49ers this offseason. The team is 4-1 when he starts this season, ...

The Houston Texans receive unfortunate injury updates for the San Francisco 49ers game regarding Nico Collins and Christian ...

In his absence, Matt Hennessy projects to start at center Sunday at Houston.