The San Francisco 49ers have not been healthy this season, and with Fred Warner and Nick Bosa out for the season, they will ...

Here's the latest on San Francisco 49ers star wide receiver Brandon Aiyuk following a knee injury last season.

Head coach Kyle Shanahan on Friday told reporters wide receiver Brandon Aiyuk is making progress toward a return that could ...

San Francisco's been without its top wideout for the whole regular season. Here's what we know about his potential return.

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce ...

San Francisco 49ers head coach Kyle Shanahan revealed on Friday that the team could open the 21-day practice window of wide ...

Once the 49ers make the aforementioned transaction, be it next week or beyond that point, the team will have a 21-day window in which to evaluate Aiyuk in practice to determine his return to action.

San Francisco general manager John Lynch said Thursday that he has both hope and "evidence" that Aiyuk (knee) will soon be ready to make his 2025 debut, David Lombardi of SFStandard.com reports.

The 49ers boast the NFL’s top-ranked passing offense (271.3 yards per game) but could use another veteran downfield threat like Aiyuk, who was a second-team All-Pro during his last full season in 2023 ...