The San Francisco 49ers have not been healthy this season, and with Fred Warner and Nick Bosa out for the season, they will ...

Head coach Kyle Shanahan on Friday told reporters wide receiver Brandon Aiyuk is making progress toward a return that could ...

Here's the latest on San Francisco 49ers star wide receiver Brandon Aiyuk following a knee injury last season.

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce ...

Kyle Shanahan’s San Francisco 49ers lead the NFC West, even without one of Brock Purdy and Mac Jones’ key weapons on the ...

If the 49ers win Sunday in Houston, they’ll match their overall win total from last season and they’ll be alone atop the NFC ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

A week after the San Francisco 49ers improbably dominated the NFL's second-ranked offense, they'll be given a far less ...

There haven't been many NFL teams this season who have surpassed their early expectations quite like the Los Angeles Rams ...

The Sharks (1-5-2) pulled Askarov with just over two minutes left in the third period for the extra skater, and managed a ...

Purdy last spoke to the media on Sept. 30, although he did have a conversation with NBC sideline reporter Melissa Stark when ...