LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.
As microbes invade the human body, phagocytic cells such as macrophages spring into action to clear the intruders. These cells extend arm-like projections and wrap them around the microbes before ...
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen ...
FAMU-FSU College of Engineering researchers have created a new method for studying protein degradation within immune cells that uses engineered microparticles to track and analyze degradation ...