Iowa State listed 14 players as out ahead of the matchup against Colorado, including defensive backs Jontez Williams, Jeremiah Cooper and Khijohnn Cummings-Coleman – plus defensive back Eddie Lemos. This defense can't afford to lose any more pieces, and if Orange is seriously injured, that will set the Cyclones back severely.

Colorado football secured a much-needed victory by upsetting No. 21 Iowa State at home. Here is how the Buffs' best win of the season went down.

There is more Big 12 conference action as No. 21 Iowa State visits Colorado Saturday afternoon at Folsom Field in Boulder, Colorado.

When the season began, this looked like the hardest game on BYU’s schedule. Don’t let Iowa State's back-to-back losses fool you, it still might be. Iowa State i

Preview the Oct. 25 matchup between the Iowa State Cyclones and BYU Cougars with predictions, odds, over/under, spread, betting lines and more.