Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce ...

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

While the San Francisco 49ers have gained an early edge with victories against fellow 5-2 rivals Los Angeles and Seattle, right tackle Colton McKivitz knows a Week 8 visit to Houston offers a unique ...

The San Francisco 49ers got extremely lucky finding Eddy Pineiro after the year started. He's been even better than Kyle Shanahan thought he'd be.

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy.

San Francisco 49ers head coach Kyle Shanahan detailed the team's latest injury report, opened up about his pregame speeches, ...

The Houston Texans receive unfortunate injury updates for the San Francisco 49ers game regarding Nico Collins and Christian ...

Let's imagine an alternate reality in which Kyle Shanahan had stuck to his gut and drafted Mac Jones instead of Trey Lance ...

The Patriots' schedule ranking is the second easiest in the league this year (behind the 49ers), according to Sharp Football.

The 49ers' top quarterback has missed five of seven games this season so far. Here's the latest on his status for Week 8.

In a new profile from the Athletic’s Mike Silver, several Niners stars heaped praise on Saleh for his impact on the 49ers ...