Head coach Kyle Shanahan on Friday told reporters wide receiver Brandon Aiyuk is making progress toward a return that could ...

The San Francisco 49ers take on the Houston Texans at 10 a.m. PT on Sunday, Oct. 26 at NRG Stadium in Houston.

Those who were declared out Sunday were quarterback Brock Purdy (toe), center Jake Brendel (hamstring), edge rusher Bryce Huff (hamstring), wide receiver Ricky Pearsall Jr. (knee) and defensive ...

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

While the San Francisco 49ers have gained an early edge with victories against fellow 5-2 rivals Los Angeles and Seattle, right tackle Colton McKivitz knows a Week 8 visit to Houston offers a unique ...

Kirk Cousins might get another shot. Falcons starting quarterback Michael Penix Jr. is questionable to play against the ...

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy.

The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They ...

San Francisco 49ers fans received very promising news on star wide receiver Brandon Aiyuk. According to San Francisco ...

The 2010 Wolf Pack team that ruined the Broncos’ undefeated season will be honored on Friday night at Mackay Stadium.

San Francisco 49ers head coach Kyle Shanahan detailed the team's latest injury report, opened up about his pregame speeches, ...