Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, No. 6 (Mar. 16, 1999), pp. 2970-2975 (6 pages) Heterozygosity for germ-line mutations in the DNA mismatch ...
Figure 1: Structural view of DNA polymerase I and key residues in this study. Since mutators fail to transition efficiently from the partially closed to the closed conformation, our results indicate ...
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