Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

A new study uses fMRI and mouse models to identify synaptic hypoconnectivity and immune hyperconnectivity autism subtypes.

Peptides have gradually emerged as some of the most intriguing molecular tools in contemporary biochemical research. Their constructional versatility, small size, and potential to interact with highly ...

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite the syndrome stemming from an altered genetic code for the single protein ...

For more than two decades, the genetics of autism seemed to splinter in every direction. Each new sequencing study added ...

The screen worked, flagging expected cancer genes. But it also kept returning something that seemed impossible: genes for synapses, glutamate receptors, and neural signaling pathways. “We absolutely ...

The schematic illustrates biological synaptic transmission (action potential–presynaptic stimulation–channel opening–neurotransmitter release–postsynaptic current) and its electronic emulation: a ...

(A) The volcano plot illustrating differentially expressed genes (DEGs) in the AAVT42-BDNF treatment and AAVT42-GFP hippocampus. Dotted lines highlighting the P-value = 0.05 (y-axis) and fold change = ...

Scientists discovered that sleep deprivation damages a key brain circuit responsible for social memory, making it harder to recognize familiar individuals. In laboratory studies, caffeine restored ...