A new method can test the activity of thousands of RNA enzymes, called ribozymes, in a single experiment. The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA ...

SANTA CRUZ, CA — Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction ...

Which came first, nucleic acids or proteins? This question is molecular biology’s version of the “chicken-or-the-egg” riddle. Genes made of nucleic acids (DNA or RNA) contain the instructions for ...

Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells. RNA molecules are real all-rounders. They transfer the genetic information from ...

RNA world vs. modern world. Present-day organisms follow the central dogma: DNA (or RNA) encode genetic information, whereas cellular functions are carried out by proteins. In an RNA world, RNA would ...

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, ...

The GlmS enzyme, which is involved in GlcN6P synthesis, is translated from mRNA containing a ribozyme sequence. GlcN6P activates the ribozyme cleaving the mRNA sequence and turning enzyme production ...

Collaborative research by the University of Tokyo and RIKEN Center for Biosystems Dynamics Research has led to the ...

Adeno-associated virus (AAV) gene therapy holds considerable promise for treating diseases caused by genetic defects or deficiencies, but the packaging capacity of AAV vectors limits the potential ...

The novel Cleavage High-throughput Assay (CHiTA) developed at Penn State provides a scarless method to characterize thousands of diverse small self-cleaving RNA enzymes, called twister ribozymes, in a ...