Bacillus subtilis has emerged as a pre‐eminent model organism for the study and application of protein expression and secretion, owing to its robust secretory pathways and genetic tractability. Its ...
Autophagy and lysosomal pathways orchestrate unconventional secretion of Parkinson’s disease protein
Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...
Bacterial interaction with plants and animals, symbiotic or pathogenic, involves the transfer to host cells and tissues of a range of bacterial proteins whose biochemical activities are key to ...
Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...
The researchers discovered that the lipid phosphatidylinositol-4-phosphate (PI4P)—usually scarce in the ER—acts as a ...
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Omega-3 fatty acids regulate mammary gland lipogenesis and development via Gαs-mediated cAMP–EPAC signaling pathway
The research team found that the supplementation of n-3 fatty acids significantly enhances lactation performance even in ...
New research, led by the Mayo Clinic, suggests that the open reading frame 8 (ORF8) protein is highly expressed in patients with severe coronavirus disease 2019 (COVID-19) infection. Additionally, ...
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