Vincristine, one of the naturally occurring vinca alkaloids extracted from the leaves of the periwinkle plant Catharanthus roseus, continues to play a key role in the treatment of childhood ALL since ...
This was a phase 3, open-label, randomized, multicenter study conducted at 26 centers in the United States, Canada, and Puerto Rico. Antiretroviral-naive, HIV-infected adults were randomized to ...
More information is needed to better understand variations in how the drug affects individual patients. The review also offers insights into how the medication affects people with liver and renal ...
This was a double-blind, randomised, placebo-controlled dose-escalation study. Patients were randomised in a 2:1 ratio to either candesartan cilexetil or placebo with the aim of including 14 patients ...
Phase I Trial of the Oral Antiangiogenesis Agent AG-013736 in Patients With Advanced Solid Tumors: Pharmacokinetic and Clinical Results One complete and five partial responses were achieved in 35 ...
AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined.
Credit: Shutterstock. The patient was receiving antiretroviral medication via a Roux-en-Y jejunostomy (J)-tube. Pharmacokinetic assessments are an important component of deciding which administration ...
Intelligent Bio Solutions Inc. INBS recently announced positive initial results from its Pharmacokinetic (PK) study. The study is important for supporting FDA 510(k) clearance of the company’s ...
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