Researchers have revealed that RANKL expressed by osteocytes is essential for the bone remodeling during orthodontic tooth movement. This result can facilitate the development of novel therapeutic ...

However, the role of osteocytes-mature bone cells derived from osteoblasts-in OI pathogenesis remains unclear. Specificity protein 7 (Sp7), encoded by Sp7 gene is an important transcription factor ...

Extracellular Fe 2+ and Fe 3+ modulate osteocytic viability, expression of SOST, RANKL and FGF23, and fluid flow-induced YAP1 nuclear translocation Figure 1: DMP1 mutations, osteomalacia and a ...

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say. While that may sound bad, it's ...

Radiation Research, Vol. 69, No. 1 (Jan., 1977), pp. 40-53 (14 pages) ...

Researchers at Australia's Garvan Institute of Medical Research have for the first time mapped the genetic profile of the skeleton's master regulator cells, known as osteocytes.

Pascal Buenzli receives funding from The Australian Research Council (project grant DE130101191). Natalie Sims receives funding from the National Health and Medical Research Council and The Australian ...

Type 2 diabetes mellitus (T2D) is associated with an increased risk of osteoporotic fractures. Several factors have been identified as being potentially responsible for this increased risk, including ...

Tokyo Medical and Dental University(TMDU) research team demonstrated that osteocytes have a crucial role in orthodontic tooth movement as the major source of receptor activator of nuclear factor-κB ...