Psychiatric disorders are complex, polygenic conditions characterized by patterned structural brain alterations. Whether these changes reflect transcriptional dysregulation driven by genetic risk ...

In neurodevelopmental research, within-diagnosis heterogeneity and across-diagnosis overlap necessitate a shift from case-control designs to data-driven clustering approaches. However, our ...

For the first time, researchers at the Netherlands Institute for Neuroscience and Amsterdam UMC have identified what happens in neural networks deep within the brain during obsessive thoughts and ...

A new study reveals that certain brain regions are more active in people with obsessive-compulsive disorder (OCD) during cognitively demanding tasks. The findings could help inform new ways in which ...

Obsessive compulsive disorder has many unknowns, including what causes it, why symptoms can differ so much between people, how medication and therapy for it actually work, and why treatment is ...

DEEP brain stimulation may improve quality of life in treatment-refractory OCD, but social and independence challenges often persist after surgery. New mixed-methods research suggests deep brain ...

Last week, we pulled back the curtain on what it really means to live with Obsessive Compulsive Disorder (OCD), beyond the jokes about being tidy or the throwaway lines about being ‘so OCD’. We ...

A recent study published in Nature Mental Health suggests that the brain chemical serotonin plays a key role in helping ...

In a first-of-its-kind study, researchers have found signs of inflammation within the neuro-circuitry associated with adult obsessive-compulsive disorder (OCD). The findings were reported June 21 in ...

Deep brain stimulation (DBS) involves stimulating certain parts of your brain with implanted electrodes. It’s a promising treatment for treatment-resistant OCD. The main treatments for OCD are talk ...