The nicotinic acetylcholine receptor (AChR) is assembled on the cell surface from multiple subunits produced in the endoplasmic reticulum (ER), but how these mechanisms are controlled has been unclear ...

Introduction: Cigarette smoking continues to be one of the most important behavioral causes of morbidity and mortality in the world. Varenicline, an α4β2 nicotinic acetylcholine receptor (nAChR) ...

Novel non-addicting analgetic therapies are urgently needed to reduce the use of opiates as painkillers. With the recent discovery that nicotinic acetylcholine receptors (nAChRs) in the immune system ...

Alpha Cognition Inc. (Nasdaq: ACOG), a commercial-stage biopharmaceutical company developing therapies for neurodegenerative diseases, today announced it will present new clinical insights on ...

A University of Queensland-led study has found Australian skinks have evolved molecular armor to stop snake venom from shutting down their muscles. The research has been published in the International ...