Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
Collaborating researchers have made a breakthrough discovery regarding the intricate defense systems of bacteriophages (phages)—viruses that can specifically target harmful bacteria without harming ...
To understand more fully the role of RNA and its modifications in living systems, researchers will need robust, reproducible, and accessible tools and techniques capable of identifying all RNA ...
A Japanese research team has demonstrated that the use of antisense oligonucleotides (ASOs) with modified bases and sugars can enhance the effectiveness of targeting diseases in the central nervous ...
Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, molecules called ...