Tumour suppressors safeguard the fidelity of the mitotic checkpoint by transcriptional regulation of genes that encode components of the mitotic checkpoint complex (MCC). Here we report a new role for ...
Mitotic arrest deficient 2 (MAD2) is thought to be a key component of the mitotic checkpoint, which ensures accurate chromosome segregation. Reduced expression of MAD2 protein is associated with ...
A new research paper was published in Oncotarget's Volume 15 on February 5, 2024, entitled, "Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational ...
Figure 6: Sequencing of qRT-PCR products: schematic diagram depicting the position of the qRT-PCR product that was sequenced and matched in the promoter region (−57 to −190) amplified by the primer ...
My research program focuses on two areas of cell biology: the molecular mechanisms of mammalian cell differentiation and mitotic checkpoint control. Though seemingly unrelated, both areas as described ...
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