Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Over the past two decades, correlative light and electron microscopies (CLEM), have become crucial for deciphering biological complexities across scales. A pivotal aspect of this workflow is the ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Berkeley Lab and UC Berkeley physicists' new technique offers detailed images of the small molecules and cell structures that ...

In 1931, physicists Knoll and Ruska unveiled the first electron microscope, revolutionizing science by using magnetic lenses ...

Imagine owning a camera so powerful it can take freeze-frame photographs of a moving electron—an object traveling so fast it could circle the Earth many times in a matter of a second. Researchers at ...

A comparison of experimental annular dark field (ADF)-scanning transmission electron microscopy (STEM) and electron ptychography in uncorrected and aberration-corrected electron microscopes. In the ...

A new microscope method reveals details that were difficult to see before, helping researchers study proteins, cells, and ...

Attending the RAISe+ Scheme Signing Ceremony are Professor Chen Fu-Rong (2nd left) and his research team members: Professor Hsueh Yu-Chun (1st left), Dr Chen Yan (2nd right) and Mr Chen Yuchi (1st ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...