The Los Angeles Lakers are off to a strong start, boasting a 17-7 record so far in the 2025-26 NBA Season. The team currently finds itself in the thick of things in the Western Conference playoff picture as the No.

Tipoff from Crypto.com Arena in Los Angeles is set for 10 p.m. ET. Los Angeles is the 7.5-point favorite in the latest Spurs vs. Lakers odds, while the over/under for total points scored is 241.5. Before making any Lakers vs. Spurs picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

The Lakers struggled to defend and didn't get much from their bench Wednesday night, recurring themes this month.

Spurs sign 6-foot-4 former Lakers guard to assist Victor Wembanyama originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. The San Antonio Spurs made a roster move on Friday that could pay off for the franchise in the long run.

San Antonio Spurs head coach Mitch Johnson offered a positive update on Victor Wembanyama before the next phase of the NBA Cup.

LeBron James' thrilling performance wasn't enough to lead the Los Angeles Lakers to victory on Wednesday night, falling to the San Antonio Spurs by the final score of 132-119 in the NBA Cup quarterfinals.

BOTTOM LINE: The Los Angeles Lakers take on the San Antonio Spurs in an NBA Cup in-season tournament group play matchup. The Lakers are 12-4 against Western Conference opponents. Los Angeles is sixth in the Western Conference scoring 118.3 points while shooting 50.7% from the field.

Austin Reaves addresses a key weakness the Lakers must fix after a Spurs loss exposed defensive flaws in NBA Cup play.