Skeletal muscle is the key motor system in the human body and plays a pivotal role in body metabolic regulation. With increased age, particularly in individuals over 80 years old, skeletal muscles ...

Decline in mitochondrial function is linked to decreased muscle mass and strength in conditions like sarcopenia and type 2 diabetes. Despite therapeutic opportunities, there is limited and equivocal ...

Translational proof-of-concept studies for gene therapeutics often match the payload gene sequence to the preclinical animal model as this avoids immune responses that could compromise drug efficacy.

Humans have a distinctive skeleton, and are the only bipedal great apes (the great ape species are bonobos, chimpanzees, gorillas, orangutans, and humans). While the evolution of the human skeleton ...

Male hormones (androgens), as their name implies, have an important role in promoting the formation of male sexual characteristics (secondary sexual characteristics). In addition, androgens have ...