Researchers from the National University of Singapore (NUS) have developed an electrochemical reaction manifold that promotes efficient nitrogen atom insertion into saturated carbocycles to access ...

Radical cyclization has emerged as a versatile and powerful strategy for the construction of nitrogen‐containing heterocycles, which are ubiquitous in pharmaceuticals, agrochemicals and functional ...

The catalytic conversion of 1,2,3-triazole derivatives into diverse heterocyclic frameworks has emerged as a powerful strategy in modern synthetic chemistry. Central to this approach is the controlled ...

LA JOLLA, CA—Ring-shaped chemical structures called saturated heterocycles are found in most FDA-approved drugs but are often difficult to create. Scripps Research chemists have just developed a ...

The molecular motif 1-azaspiro[3.3]heptane may look peculiar, with its two 4-membered rings that share a single carbon. But the structure can behave like a mimic of piperidine, a popular heterocycle ...