Bone marrow contains stem cells with the potential to differentiate into mature cells of various organs. We determined whether circulating stem cells have a similar potential. Biopsy specimens from ...

Metabolic-associated steatohepatitis (MASH) can cause liver damage, which can be stopped or reversed if it’s caught early. Learn more about the treatments that may help.

In vitro drug-metabolism data has been increasingly utilized in understanding and predicting pharmacokinetics in vivo. Traditionally, predictive studies have been conducted in animal models. Because ...

Donor organ shortage is still the major obstacle for the clinical application of hepatocyte transplantation in the treatment of liver diseases. However, generation of hepatocyte-like cells from ...

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed ...

In a recent study published in PNAS, researchers performed a retrospective cohort study among patients hospitalized on suspicion of coronavirus disease 2019 (COVID-19) between March and August 2020 in ...

HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...

The Greek Titan Prometheus was punished for his altruism toward mortals after giving them fire. He was chained to a rock for eternity and forced to endure watching an eagle consume his liver during ...