One main goal of anti-cancer therapies is to kill tumor cells without affecting the surrounding normal cells. Therefore, many drugs are designed to target tumor-specific antigens, which are molecules ...

In a breakthrough cancer therapy development, scientists at MIT and Harvard Medical School created a new way of designing ...

A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system – the HLA class II molecules – while accurately predicting how they display ...

Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used ...

Australian-led research is unlocking new ways for immunotherapy to better target cancer. Cancer immunotherapy has revolutionized treatment for patients, whereby the body's own immune system is ...

Next, Hollenbach wanted to know how that particular kind of HLA molecule might be preventing a person from getting symptoms. It turns out that HLA-B*15:01 recognizes pieces of other kind of SARS ...

The Transplant Company™ – a leading precision medicine company focused on the discovery, development, and commercialization ...

This paper is the first description of the three-dimensional structure of a class II human leukocyte antigen (HLA). Also known as histocompatibility antigens, the HLA molecules are present on various ...

Cancer immunotherapy has revolutionized treatment for patients, whereby the body's own immune system is harnessed to destroy cancer cells. Typically, several molecules restrain the ability of T cells ...