Insights into the role of ADGRF5 aids the understanding of glomerular disorders and significantly contributes to the advancement of future research." Unlocking the novel functions of the ADGRF5 ...

A team of scientists now reports an approach that enables the differentiation of human induced pluripotent stem (iPS) cells into mature podocytes with more than 90 percent efficiency. Linking the ...

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries — small blood vessels that regulate the movement of ions, water, and metabolites while maintaining ...

Researchers have developed the first model of kidney filtration in the lab that accurately mimics human kidney physiology. The model represents a leap in chronic kidney disease research and could help ...

Nephropathy is a major complication of diabetes. Alterations of mesangial cells have traditionally been the focus of research in deciphering molecular mechanisms of diabetic nephropathy. Injury of ...

Microalbuminuria is significant both as the earliest stage of diabetic nephropathy and as an independent cardiovascular risk factor in nondiabetic subjects, in whom it is associated with insulin ...

ADGRF5 is crucial for maintaining GFB integrity and function, with its deletion causing significant kidney defects and impaired function.

(Nanowerk News) The kidney - made up of about a million tiny units that work to filter blood, constantly rids the body of undesired waste products to form urine while holding back blood cells and ...