Chargers safety Derwin James missed most of Thursday night's victory over the Vikings, but there's a possibility he'll be back in time for Los Angeles' next game.

Safety Derwin James Jr.'s first interception of 2025 crushes Miami Dolphins' comeback hopes. Highlights from the Week 6 matchup between the Los Angeles Chargers and the Miami Dolphins during the 2025 NFL season. Watch the best plays by running back Kimani Vidal from his 138-yard game during Week 6 of the 2025 NFL season.

After the game, head coach Jim Harbaugh was asked about the injuries, but he remained secretive, as he often does. Harbaugh offered no updates initially on the three players. No updates on Derwin James (ankle), Mekhi Becton (knee) or Tarheeb Still (knee) per Jim Harbaugh.

After losing three of their last four amid many injuries, Chargers safety Derwin James Jr. says: “Get back to the fundamentals. Get back to what got us here.”