The degradation of mRNAs involves removal of the 5′ protective cap via a decapping-enzyme complex, in a largely irreversible process that commits the transcript for destruction. Understanding how the ...

In budding yeast, most cytoplasmic mRNA turnover is initiated by deadenylation 1. These messages are then either decapped and subject to 5′ → 3′ decay 2,3 or degraded by the cytoplasmic exosome 4.

Chip decapping videos are a staple of the hacking world, and few things compare to the beauty of a silicon die stripped of its protective epoxy and photographed through a good microscope. But the ...

Join us on Wednesday, March 10 at noon Pacific for the Decapping Components Hack Chat with John McMaster! We treat them like black boxes, which they oftentimes are, but what lies beneath the ...

IntelliXcap Tube Capping/Decapping & Sealing Systems from Azenta Life Sciences provide fully and semi-automated solutions for various throughput levels. The instrument range includes dependable manual ...

In eukaryotes, the decapping machinery is highly conserved and plays an essential role in controlling mRNA stability, a key step in the regulation of gene expression. Yet, the role of mRNA decapping ...