A conventional production fed-batch process involves a multi-stage seed expansion and elaborate clarification steps to isolate the protein of interest from other process impurities. The current ...
The demand for producing therapeutic recombinant proteins is generating a renewed interest in perfusion cell culture technologies, leading to the development of cell culture media that can support ...
Upstream’s Relatively Continuous Flows Raise Hopes for Continuous Purification Perfusion culture has been employed for at least 20 years in bioprocessing, but it is now catching on as the upstream ...
Researchers at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID) developed a new transient gene expression (TGE) bioprocess using a perfusion ...