Researchers at Ruhr University Bochum, Germany, identified a receptor that plays a crucial role in stress-induced motor ...

Beta3-adrenergic receptors (β3-AR) have emerged as pivotal modulators of cardiac performance, particularly in the context of heart failure. Distinct from the classical β1/β2-adrenergic signalling ...

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation ...

Salk Institute scientists discovered a relationship between killer T cell exhaustion and the body’s sympathetic—“fight-or-flight”—stress response. The research showed that beta-blockers could inhibit ...

A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...

Scientists have shown the efficacy of a new non-opioid oral painkiller known as ADRIANA, the world's first selective α2B-adrenoceptor antagonist – a receptor subtype not previously targeted for ...

When brown fat — calorie-burning adipose tissue once thought to exist only in infants — was discovered in adults 15 years ago, obesity medicine researchers started searching for ways to help people ...

OAB is commonly treated with a class of medicines called anticholinergics or antimuscarinics. These medicines block chemicals in your body that help the bladder to squeeze. By blocking these chemicals ...