Here are some tips for choosing an over-the-counter medication for headaches, body aches, fever and more.

Tylenol (acetaminophen) is one of the most commonly used over-the-counter medications for relieving pain and reducing fever. While it’s generally considered safe for most adults, older adults, ...

Alcohol use is one of those risk factors (which is why acetaminophen and alcohol don't mix). "Regular alcohol intake also ...

Older adults who take acetaminophen for pain generally or for osteoarthritis (OA) pain specifically have elevated risks for gastrointestinal, cardiovascular, and renal adverse effects. Investigators ...

When hit with a headache or fever, people often reach for over-the-counter painkillers like acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) as their first line of defense. Used ...

Acetaminophen recently became a polarizing political topic and target. It's important to remove the political filters and pull the lens back to see acetaminophen for what it actually is—a synthetic ...

This story was originally published on April 18, 2025, and has been updated. On Monday, President Trump announced that the Food and Drug Administration would be discouraging the use of acetaminophen ...