Expert recap and game analysis of the San Francisco 49ers vs. Atlanta Falcons NFL game from October 19, 2025 on ESPN.

The San Francisco 49ers finally got the run game going in a 20-10 win over the Atlanta Falcons over the weekend.

The Falcons and 49ers game will kick off at 8:20 p.m. ET on Sunday, Oct. 19. The San Francisco 49ers vs. Atlanta Falcons game will be broadcast on NBC on Sunday night. Streamers can also catch the game on Peacock or with Fubo, which comes with a free trial.

The 49ers won't have one of their top rookies tonight when they face the Atlanta Falcons on Sunday Night Football.

Quarterback Brock Purdy remains limited by a toe injury and could miss his fourth straight game for the San Francisco 49ers.

The Atlanta Falcons are 3-2 after five weeks, but despite having the NFL's No. 1 ranked defense, those around the league have been hesitant to buy in just yet. That narrative could change if the Falcons are able to defeat the San Francisco 49ers on the road in Week 7.

The NFL announced it is suspending Greenlaw for Denver’s Week 8 game against the Cowboys because the linebacker “chased after referee Brad Allen and verbally threatened him as he tried to leave the field,” the league’s statement read. According to multiple reports, Greenlaw immediately appealed the suspension.

Chase Lucas hasn't played much, but he's made an outsized impact for the 49ers, including two game-sealing plays.