Not long after nearly losing a fumble on a sack, Mac Jones finally unravels for the 49ers, tossing a deep pick to Jamel Dean that just might seal a home victory for Tampa Bay, which is getting heroic stuff from its own gunslinger in Baker Mayfield:

The injury report for the Tampa Bay Buccaneers (4-1) heading into their game against the San Francisco 49ers (4-1) features 11 players. The contest starts at 4:25 p.m. ET on Sunday, Oct. 12, at Raymond James Stadium. Game time: 4:25 p.m. ET

Despite the onslaught of injuries to begin the season, the Tampa Bay Buccaneers have started hot at 4-1 after a big victory over the Seattle Seahawks in Week 5

Preview the San Francisco 49ers' NFL week 6 matchup with the Buccaneers, including betting odds, tips, trends, and game information.

After spending the first two decades of his career with the New England Patriots, Tom Brady took his talents to the Tampa Bay Buccaneers for his last three years in the NFL. The three-time AP MVP won six Super Bowls alongside Bill Belichick in New England before securing one final championship in Tampa in 2021.

The Seattle Seahawks will host the Tampa Bay Buccaneers on Oct. 5 at Lumen Field. The Seahawks and Buccaneers, both 3-1, are celebrating their 50th seasons as members of the NFL's 1976 expansion.

Buccaneers wideouts Mike Evans and Emeka Egbuka are game-time decisions for MNF vs Lions, per ESPN’s Adam Schefter.